ea0037gp.18.05 | Pituitary–Basic and IGF-1 | ECE2015
Ibanez-Costa Alejandro
, Gahete Manuel D
, Rivero-Cortes Esther
, Rincon-Fernandez David
, Nelson Richard
, Beltran Manuel
, de la Riva Andres
, Japon Miguel A
, Venegas-Moreno Eva
, Galvez Maria Angeles
, Garcia-Arnes Juan A
, Soto-Moreno Alfonso
, Morgan Jennifer
, Tsomaia Natia
, Culler Michael D
, Dieguez Carlos
, Castano Justo P
, Luque Raul M
Pituitary adenomas comprise a heterogeneous group of tumours causing serious comorbidities, which would benefit from identification of novel, common molecular/cellular biomarkers and therapeutic targets. The ghrelin system comprises a complex molecular family with multiple functions, and some of its components have been linked to development of various endocrine-related cancers. In this work we aim at better delineating the patho-physiological significance of the ghrelin regul...